arrayed primer extension (apex) microarray approach (Asper Biotech Ltd)

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Asper Biotech Ltd arrayed primer extension (apex) microarray approach
Arrayed Primer Extension (Apex) Microarray Approach, supplied by Asper Biotech Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/arrayed+primer+extension+(apex)+microarray/arrayed+primer+extension++apex++microarray+method/pm21521029-67-8-5
Average 90 stars, based on 1 article reviews

arrayed primer extension (apex) microarray approach - by Bioz Stars, 2026-10

90/100 stars

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Microarray:

Article Title: Molecular and phenotypic investigation of a New Zealand cohort of childhood-onset retinal dystrophy.
Article Snippet: Funding information Cure Kids, New Zealand, Grant/Award Number: 3584; Ombler Charitable Trust, Grant/Award Number: 3626039; Retina New Zealand, Grant/Award Number: 3625913; Save Sight Society of New Zealand, Grant/Award Number: 3625915 Abstract Inherited retinal diseases are clinically heterogeneous and are associated with nearly 300 different genes.. In this retrospective, observational study of a consecutive cohort of 159 patients (134 families) with childhood-onset (<16 years of age) retinal dystrophy, molecular investigations, and in-depth phenotyping were performed to determine key clinical and molecular characteristics.. The most common ocular phenotype was rod-cone dystrophy in 40 patients.

Article Title: Spectrum of Disease Severity in Nonsyndromic Patients With Mutations in the CEP290 Gene: A Multicentric Longitudinal Study
Article Snippet: Total genomic DNA was extracted from peripheral blood using standard protocols or the DNeasy Blood and Tissue Kit (QIAGEN). .. Older analyses were performed by an Arrayed Primer Extension (APEX)-based genotyping microarray ( www.asperbio.com ; Asper Biotech, Ltd.) on different chip versions that comprised known mutations associated with LCA and EOSRD (LCA chip versions 2004–2009 ). ..

Article Title: Reevaluation of the Retinal Dystrophy Due to Recessive Alleles of RGR With the Discovery of a Cis-Acting Mutation in CDHR1.
Article Snippet: .. Arrayed primer extension (APEX) microarray (Asper Biotech Ltd., Tartu, Estonia) for previously identified Leber congenital amaurosis (LCA) disease-associated mutations (including the RGR p.Ser66Arg mutation), and subsequent direct Sanger sequencing of CDHR1 exon 17 using standard PCR and sequencing techniques (primers available on request), were used in one individual. ..

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Article Title: Genotyping microarray for CSNB-associated genes.
Article Snippet: For the arrayed primer extension (APEX) microarray (Asper Biotech Ltd., Tartu, Estonia), 126 sequence variants were selected from multiple sources, including recent mutations identified in our laboratory and mutations or putative polymorphisms found in a comprehensive literature and database search.4 DNA was extracted by standard methods (detailed information is available on request) and mutation analyses of CABP4, CACNA1F, CACNA2D4, GRM6, NYX, and RHO were performed as described recently.8–11 Mutation analyses for GNAT1 and PDE6B were performed by PCR-amplification of the 8 coding exons of GNAT1 in 5 amplicons and the 22 coding exons of PDE6B in 20 fragments, by applying a polymerase enzyme (HotFire, Tartu, Estonia) and subsequently using direct sequencing (detailed conditions on request).

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